Tuesday, 1 October 2013

6-Mercaptopurine (6-MP, Purinethol) For the Treatment of Cancer

Description
6-Mercaptopurine is chemotherapy given for the treatment of all acute lymphoblastic leukemia.

How It Is Given
It is taken by mouth most often as a single daily dose, or for a set number of days per month.  It is best taken on an empty stomach which means 1 hour before or 2 hours after meals.

Common Side Effects
  • Reduced blood counts

Less Common Side Effects
  • Mouth sores
  • Loose, frequent stools
  • Fever
  • Nausea and vomiting
  • Skin rash
  • Kidney changes may occur
  • Liver changes may occur
  • Decreased appetite

Call Your Health Care Provider if You Develop
  • Fever greater than 100.8° F
  • Trouble urinating or burning with urination
  • Nausea or vomiting not controlled by medicine

Special Concerns
  • Allopurinol should be stopped before taking 6-MP.
  • Blood tests will be taken to check your liver and kidney function.

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